Mitral Valvular Coaptation-Zone Area Is Associated with the Severity of Atherosclerosis Assessed by Cardio-Ankle Vascular Index

Preservation of the mitral valve (MV) size is essential for function, and a reduced MV coaptation-zone area increases risk developing functional regurgitation (FMR). We aimed to determine if leaflet areas were associated with severity atherosclerosis assessed by cardio-ankle vascular index (CAVI) in patients normal left ventricle (LV) systolic function real-time 3D echocardiography (RT3DE).We performed RT3DE analysis 66 LV ejection fraction who underwent 2D CAVI. measured custom software indexed body surface (BSA). The associations clinical factors mean CAVI evaluated univariable multivariable linear regression analyses.On analysis, area/BSA was significantly age (r = -0.335, P 0.0069) -0.464, < 0.001), -0.626, hypertension dyslipidemia E/e' -0.740, 0.001). On independently only (standardized coefficient -0.611, 0.001) -0.74, 0.001).In size, might be according advancing atherosclerosis. Patients at increased FMR.